Volume 11, Issue 1 (6-2024)
J Prevent Med 2024, 11(1): 40-49 |
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Ethics code: IR. bums. REC. 1399.174
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Norouzi R, Adnani Sadati S J, Ahmadi R, Afzalipour R, Siyadatpanah A, Sadeghinasab J et al . Seroprevalence of Toxoplasma Gondii Infection in Patients With Thyroid Dysfunction Compared to Healthy People in Yazd, Iran. J Prevent Med 2024; 11 (1) :40-49
URL: http://jpm.hums.ac.ir/article-1-756-en.html
URL: http://jpm.hums.ac.ir/article-1-756-en.html
Roghayeh Norouzi * 
1, Seyed Jafar Adnani Sadati2 , Reza Ahmadi3 , Reza Afzalipour4 , Abolghasem Siyadatpanah5 , Javad Sadeghinasab6 , Ahmad Negahban7
1, Seyed Jafar Adnani Sadati2 , Reza Ahmadi3 , Reza Afzalipour4 , Abolghasem Siyadatpanah5 , Javad Sadeghinasab6 , Ahmad Negahban7
1- Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran.
2- Department of Microbiology Immunology and Parasitology, Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran.
3- Department of Internal Medicine, Infectious Diseases Research Center, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
4- Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
5- Department of Microbiology, Infectious Diseases Research Center, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
6- Department of Pediatrics, School of Medicine, Gonabad University of Medical Science, Gonabad, Iran.
7- Department of Health Information Technology, Ferdows Faculty of Medical Sciences, Birjand University of Medical Sciences, Birjand, Iran.
2- Department of Microbiology Immunology and Parasitology, Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran.
3- Department of Internal Medicine, Infectious Diseases Research Center, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
4- Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
5- Department of Microbiology, Infectious Diseases Research Center, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
6- Department of Pediatrics, School of Medicine, Gonabad University of Medical Science, Gonabad, Iran.
7- Department of Health Information Technology, Ferdows Faculty of Medical Sciences, Birjand University of Medical Sciences, Birjand, Iran.
Abstract: (500 Views)
Objective Human toxoplasmosis is a disease caused by Toxoplasma gondii, which is associated with many disorders in different human organs. However, the association between toxoplasmosis and thyroid dysfunction is not been fully known. Therefore, this study aims to asses the relationship of toxoplasmosis with thyroid dysfunction in patients compared to healthy people in Yazd, Iran.
Methods This study was conducted on 82 patients with thyroid dysfunction (78 females, 4 men) and 801 healthy controls (747 females, 54 men) in Yazd, center of Iran. The sera obtained from patients were tested for the presence of T. gondii by detecting specific IgG antibodies. In this regard, triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone thyrotropin (TSH) levels were measured by the ELISA method.
Results In this study, anti-Toxoplasma IgG antibody was detected in 12 patients with thyroid dysfunction (14.63%) and 146 healthy people (18.23%). The results of statistical analysis showed that no significant difference in the prevalence of anti-Toxoplasma IgG antibody in people with hypothyroidism and the control group (P=0.54).
Conclusion There is no significant differences in the seroprevalence of T. gondii in patients with hypothyroidism and hyperthyroidism compared to healthy people in Yazd, Iran. Based on these observations, we recommended further prospective studies to more clarify the relationship between thyroid dysfunction and toxoplasmosis.
Methods This study was conducted on 82 patients with thyroid dysfunction (78 females, 4 men) and 801 healthy controls (747 females, 54 men) in Yazd, center of Iran. The sera obtained from patients were tested for the presence of T. gondii by detecting specific IgG antibodies. In this regard, triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone thyrotropin (TSH) levels were measured by the ELISA method.
Results In this study, anti-Toxoplasma IgG antibody was detected in 12 patients with thyroid dysfunction (14.63%) and 146 healthy people (18.23%). The results of statistical analysis showed that no significant difference in the prevalence of anti-Toxoplasma IgG antibody in people with hypothyroidism and the control group (P=0.54).
Conclusion There is no significant differences in the seroprevalence of T. gondii in patients with hypothyroidism and hyperthyroidism compared to healthy people in Yazd, Iran. Based on these observations, we recommended further prospective studies to more clarify the relationship between thyroid dysfunction and toxoplasmosis.
Type of Study: Orginal |
Subject:
Epidemiology
Received: 2024/02/15 | Accepted: 2024/03/6 | Published: 2024/04/1
Received: 2024/02/15 | Accepted: 2024/03/6 | Published: 2024/04/1
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