Journal of Preventive Medicine

Introduction: Septicemia is one of the main causes of mortality. Blood culture is the most common method for diagnosis of bacterial systemic infections. Gram negative bacterial infections cause mortality due to unavailability of new methods for rapid diagnosis and appropriate treatment. This study was conducted to investigate the Prevalence and antibiogram pattern of gram negative bacteria isolated from blood cultures in Shahid mohammadi hospital in Bandar Abbas city.

Methods: In this cross-sectional descriptive study, blood specimens were collected from 2845 suspected to septicemia patients hospitalized in Shahid Mohammadi hospital and were studied for  bacteria causing septicemia .The isolated bacteria were identified using conventional methods and susceptibility pattern to antibiotics were determined by using Kirby- Bauer method according to method of Clinical and Laboratory Standard Institute (CLSI). Data were analyzed by SPSS 13.

Results: In this study from 2845 patients suspected to septicemia, 134 (4.71%) cases of gram negative bacteria were isolated. Most of gram negative bacteria were isolated from medical emergency (60.4%), internal medicine (17.2%) and ICU (14.9%) wards. E.coli (26.1%), Pseudomonas spp.(21.6%), Acinetobacter spp.(17.2%), and Klebsiella spp.(12.6%) were the predominant pathogens. Results of antibiotic sensitivity test indicated high resistance to Ceftazidim (83.3%) and Ceftriaxon (72%), and low resistance to Ciprofloxacin (32.5%) and Imipenem (36.3%).

Conclusion: Results showed that resistance to antibiotics is increasing in the studied population. Therefore proper and rapid diagnosis of pathogenic agents and treatment of patients according to antibiogram pattern can reduce mortality rate, period of hospitalization and treatment costs.