Volume 12, Issue 1 (spring 2025)
J Prevent Med 2025, 12(1): 87-106 |
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Gaeini A A, Zafarmand O, Hosseini M. The Effect of Aerobic Training on Resistin and Insulin Resistance in Type 2 Diabetics: A Systematic Review and Meta-Analysis. J Prevent Med 2025; 12 (1) :87-106
URL: http://jpm.hums.ac.ir/article-1-810-en.html
URL: http://jpm.hums.ac.ir/article-1-810-en.html
1- Professor of Department of Exercise Physiology, Faculty of Sports Science, University of Tehran, Tehran, Iran.
2- MSc in Exercise Physiology, Department of Physical Education and Sports Science, University of Yasouj, Yasouj, Iran.
3- Assistant Professor of Physical Education, Department of Physical Education, Farhangian University, P.O. Box 14665-889, Tehran, Iran.
2- MSc in Exercise Physiology, Department of Physical Education and Sports Science, University of Yasouj, Yasouj, Iran.
3- Assistant Professor of Physical Education, Department of Physical Education, Farhangian University, P.O. Box 14665-889, Tehran, Iran.
Abstract: (789 Views)
Introduction: The increase of diabetes in the world and the positive results of excercise and physical activity on the factors related to this disease have been considered. Resistin is a factor secreted from adipose tissue that is related to type 2 diabetes. Therefore, the aim of this study was the effect of aerobic exercises on insulin resistance in type 2 diabetics.
Methods: The present study is a systematic review and meta-analysis. A systematic review of English and Farsi articles published in PubMed, Web of Science, Scopus, Sid and Magiran databases was conducted until September 2024. Mean difference and 95 درصد confidence interval (CI) were calculated using random effect model. Heterogeneity was evaluated using the (I2) test, and publication bias was evaluated by visual analysis of the funnel plot and Egger's test. A total of 14 studies with (15 interventions) and 456 type 2 diabetic subjects were meta-analyzed.
Findings: The results showed that aerobic training caused a significant decrease in resistin [SMD=-1.087 (-0.059 to -2.114), P=0.038] and insulin resistance [SMD=-0.875 (-0.282 to -1.467), P=0.004] compared to the control group in type 2 diabetics.
Conclusion: The results showed that aerobic exercises in type 2 diabetics who are overweight and obese cause a decrease in resistin and insulin resistance in a way that causes a decrease in their weight and body fat percentage. Therefore, aerobic exercises can be suggested to these people as a practical and non-pharmacological solution to reduce type 2 diabetes.
Methods: The present study is a systematic review and meta-analysis. A systematic review of English and Farsi articles published in PubMed, Web of Science, Scopus, Sid and Magiran databases was conducted until September 2024. Mean difference and 95 درصد confidence interval (CI) were calculated using random effect model. Heterogeneity was evaluated using the (I2) test, and publication bias was evaluated by visual analysis of the funnel plot and Egger's test. A total of 14 studies with (15 interventions) and 456 type 2 diabetic subjects were meta-analyzed.
Findings: The results showed that aerobic training caused a significant decrease in resistin [SMD=-1.087 (-0.059 to -2.114), P=0.038] and insulin resistance [SMD=-0.875 (-0.282 to -1.467), P=0.004] compared to the control group in type 2 diabetics.
Conclusion: The results showed that aerobic exercises in type 2 diabetics who are overweight and obese cause a decrease in resistin and insulin resistance in a way that causes a decrease in their weight and body fat percentage. Therefore, aerobic exercises can be suggested to these people as a practical and non-pharmacological solution to reduce type 2 diabetes.
Type of Study: Review |
Subject:
Occupational Medicine
Received: 2024/12/31 | Accepted: 2025/04/13 | Published: 2025/10/5
Received: 2024/12/31 | Accepted: 2025/04/13 | Published: 2025/10/5
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